Edit AnswerTags: Nico Hill2's Answer to What are the ethical challenges related to whole brain emulation?

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Unless there was a way to cryptographically ensure otherwise, whoever runs the emulation has basically perfect control over their environment and can reset them to any state they were previously in. This opens up the possibility of powerful interrogation and torture of digital people.

Imperfect uploading might lead to damage that causes the EM to suffer while still remaining useful enough to be run for example as a test subject for research. We would also have greater ability to modify digital brains. Edits done for research or economic purposes might cause suffering. See this fictional piece for an exploration of how a world with a lot of EM suffering might look like.

These problems are exacerbated by the likely outcome that digital people can be run much faster than biological humans, so it would be plausibly possible to have an EM run for hundreds of subjective years in minutes or hours without having checks on the wellbeing of the EM in question.